Symbol
Name
ID

Serpina3i
serine (or cysteine) peptidase inhibitor, clade A, member 3I
MGI:2182841

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Sinusitis

Chronic sinusitis

Hepatosplenomegaly

Pancreatitis

Recurrent pneumonia

Asthma

Nontuberculous mycobacterial pulmonary infection

Recurrent Burkholderia cepacia infections

Recurrent Haemophilus influenzae infections

Recurrent Staphylococcus aureus infections

Recurrent Aspergillus infections

Recurrent respiratory infections

Recurrent bronchopulmonary infections

Recurrent lower respiratory tract infections

Disease(s) Associated with SERPINA3

cystic fibrosis

Mouse Phenotypes		white adipose tissue inflammation	decreased T cell proliferation	decreased CD8-positive, alpha-beta memory T cell number	decreased leukocyte cell number	abnormal memory T cell morphology	abnormal response to infection
Availability	Mouse Genotype	white adipose tissue inflammation	decreased T cell proliferation	decreased CD8-positive, alpha-beta memory T cell number	decreased leukocyte cell number	abnormal memory T cell morphology	abnormal response to infection
	Serpina3c^em1Smoc/Serpina3c^em1Smoc
	Serpina3g^tm1.1Arp/Serpina3g^tm1.1Arp
	Serpina3i^em1(IMPC)J/Serpina3i^em1(IMPC)J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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